Furthermore, the researchers previously revealed that FOXM1 interacted with MELK to block radiotherapy response [134], and in the present study, IR-induced upregulation of FOXM1 level was attenuated by ALKBH5 inhibition, implicating other possible pathway of ALKBH5-mediated radio-resistance in GBM [133]. Here, FOXM1 is linked to glioblastoma.