RT alone increased IFN-γ in tumors, while ATRi QDx3 attenuated RT-induced IFN-γ (Figure 4B), which is entirely consistent with our prior finding that ATRi QDx3 attenuated RT-induced increases in tumor-infiltrating, IFN-γ–competent CD8+ T cells at this time point (17). This evidence concerns the gene IFNG and neoplasm.