Our results showed that CA-IX was diffusely strong positive staining in all of 12 MCRN-LMPs and 33 cystic and solid parts of ccRCCs with cystic component similar to MCRN-LMP, which illustrates that these tumors are a subtype of ccRCC with activation of HIFα pathway due to VHL inactivation, as mentioned in some studies [3, 23–26]. Here, CA9 is linked to nonpapillary renal cell carcinoma.