All patients with MCRN-LMP and ccRCC with cystic component similar to MCRN-LMP had no VHL syndrome (family history; retinal, cerebellar, and spinal hemangioblastomas; pheochromocytoma; pancreatic tumors and cysts; endolymphatic sac tumors) or other genetic syndromes. Here, PDLIM7 is linked to hereditary pheochromocytoma-paraganglioma.