All patients with MCRN-LMP and ccRCC with cystic component similar to MCRN-LMP had no VHL syndrome (family history; retinal, cerebellar, and spinal hemangioblastomas; pheochromocytoma; pancreatic tumors and cysts; endolymphatic sac tumors) or other genetic syndromes. The gene discussed is PDLIM7; the disease is endolymphatic sac tumor.