KMT2A and acute lymphoblastic leukemia: For instance, the oncogenic fusion protein KMT2A-MLLT1 (also known as MLL1-ENL1), which has been recurrently observed in ALL, AML, and MLL (mixed-lineage leukemia) [103], forms aberrant SWI/SNF complexes named EBAFb (ENL-associated BAF-containing BAF250b) [104].