According to an integration of whole-exome sequencing (WES) and whole-genome sequencing (WGS) studies in over 2000 patients, the top mutated SWI/SNF genes in DLBCL are ARID1A (8.6%), ARID1B (7.0%), BCL7A (6.1%), SMARCA4 (5.2%), and ACTB (4.8%) (Fig. 2C) [7, 8, 82, 83]. Here, BCL7A is linked to diffuse large B-cell lymphoma.