Mechanically, HLA complex P5 (HCP5) and myocardial infarction associated transcript (MIAT), upregulated the expression of PD-L1/CD274 by sponging miR-150-5p, which is regulated by the transcriptional axis of lip-polysaccharides (LPS) -CCCTC binding factor (CTCF). The gene discussed is CTCF; the disease is myocardial infarction.