MLXIPL and hepatocellular carcinoma: Although the results of this study are partially consistent with the findings of Dong et al., we studied the biological behaviors of uncontaminated Hep3B and Huh7 cell lines, which are more convincing than the SMMC-7721 and HepG2 cell lines studied by Dong et al. Moreover, we investigated the regulation of MLXIPL on the invasion and migration of HCC cells, providing a more comprehensive theoretical basis for the role of MLXIPL in HCC.