TNFRSF11B and diabetes mellitus: As seen in a study comparing serum OPG concentration between 45 patients with diabetes and 45 healthy age, and sex-matched individuals, higher levels of OPG (the mean level of OPG in diabetic patients was 12.9 ± 5.7 pmol/L and the mean level of OPG in non-diabetic controls was 8.6 ± 0.5 pmol/L) showed a positive correlation with coronary artery calcium score, although the reported OR contradict their findings [32].