AHR and acute respiratory distress syndrome: Furthermore, a flow cytometry analysis of RORcreAhrfl/fL mice showed that the I3C-mediated induction of Th22 cell expansion was dependent on the AhR expression on RORγt+ cells during ARDS but that there were no changes in the pathogenic Th17 population in the RORcreAhrfl/fL+LPS group versus the RORcreAhrfl/fL+LPS+I3C group.