miR-29b-2-5p has binding affinity for both IL-17a and the AhR 3′UTR region, but it does not have binding affinity for IL-22 and RORc, suggesting that the alteration in their gene expression when treating ARDS with I3C may be a downstream effect of miR-29b-2-5p binding to IL-17a and/or AhR. This evidence concerns the gene IL22 and acute respiratory distress syndrome.