Furthermore, we found that the I3C-mediated shift in the Th17 RORγt +IL-17a+IL-22+ cells and Th22 IL-17a-IL-22+ lymphocytes was dependent on the AhR on RORγt+ cells and was orchestrated by miRNA-29b-2-5p, the role of which in ARDS has not been studied previously. This evidence concerns the gene IL17A and acute respiratory distress syndrome.