Additionally, studies investigating cerebrovascular haemodynamics should measure apolipoprotein‐E4 (APOE‐4) status, a genetic risk factor for Alzheimer's disease, which further accelerates age‐related changes in biomarkers of Alzheimer's disease in perimenopausal and postmenopausal women (Mishra et al., 2021). Here, APOE is linked to Alzheimer disease.