INS and Headache: We found one pleiotropic locus between headache and glucose (12p13.32) and fasting proinsulin (11q13.4), and several pleiotropic loci between headache and FI (8p23.1, 9q33.1, and 14q32.12-q32.13) and HbA1c (1q32-q23.1, 2q34, 5q31.1, 7p22.3, 8p23.1-p22, 12p13.32, and 14q32.12-q32.13).