These seven lead SNPs were mapped to the nearest protein-coding genes of MANBA, ELFN1, AP3B1, HSPA4, MANBA, NBEAL1, and GOLGA6A. Six of these lead SNPs or loci are novel for both headache and glycemic traits since they were not previously implicated in these traits, while one locus (MANBA) being novel for headache but not FG. This evidence concerns the gene HSPA4 and Headache.