ADAMTS9 and ischemic stroke: The ADAMTS9 gene, located near lead SNP rs4611812, encodes the ADAMTS-9 protein, a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family, which may also play a key role in the pathophysiological processes underlying the diseases of the central nervous system like ischemic stroke and spinal cord injury (Lin et al. 2017).