BCL2 and lymphoma: We focused on BCL2 as this was the gene with the highest number of patients with TFA-BT NCVs in PCAWG and found that lymphoma patients with TFA-BT NCVs in the BCL2 promoter showed a marked allelic expression imbalance of BCL2 not observed in patients with other or no NCV in the BCL2 promoter (Supplementary Fig. 3b).