In addition, we obtained samples with immunostaining from human protein atlas (HPA)64, and found the stained sample from CRC patient (id: 3264) we found the ASPN stain tended to enrich at tumor boundary, while POSTN, representative marker of another subtype of fibroblasts, tended to enrich at tumor stroma (Supplementary Fig. 6g). The gene discussed is POSTN; the disease is neoplasm.