Mean DNA methylation levels over − 108, − 106, − 96, − 86, − 80, − 65, and − 61 CpG sites of the ATG5 gene were increased in SDB patients with memory impairment versus those without memory impairment (3.07 ± 2.33 versus 2.3 ± 0.87%, adjusted p = 0.039, Fig. 3G). This evidence concerns the gene ATG5 and memory impairment.