SQSTM1 and obstructive sleep apnea syndrome: In five OSA patients whose blood samples were obtained again after more than 6-month CPAP treatment, p62( +) percentage of blood CD16+ neutrophils was reduced (29.2 ± 27% versus 95.7 ± 9%, p = 0.004, Fig. 2A), while none of the other parameters showed normalization after CPAP treatment.