GMNN and neoplasm: Of the nine samples for which a fHR score could not be determined, three were excluded because the amount of DNA damage in S–G2 phase cells did not exceed the set thresholds (>10% for chemo-naïve, >30% for NACT-treated samples), three because they did not have enough geminin-positive tumor cells (threshold of >50 cells), and another three due to failed staining or imaging.