Consistent with the tumor size and weight, DIRAS3 and ULK1 expression in tumor tissues were significantly overexpressed in tumor tissues in the sh-RNF157-AS1 group compared with the sh-NC group, while there was no significant difference between the pLV-RNF157-AS1 and pLV-NC groups in the expression of DIRAS3 and ULK1 in tumor tissues (Fig. 8G, H). The gene discussed is RNF157; the disease is neoplasm.