TP53 was the most frequently mutated gene in our patient cohort and mutations in this gene were found in the tumors of 8 subjects: five patients diagnosed with osteosarcoma, one patient with alveolar rhabdomyosarcoma, one patient with Ewing sarcoma and other with solitary fibrous tumor (Table 3). The gene discussed is TP53; the disease is alveolar rhabdomyosarcoma.