Indeed, our transcriptomic data revealed that the expression of genes involved in bacterial phagocytosis, such as Marco, Lrp1, Nr1h3, and Pparg, in PBMCs of septic mice tended to increase with the infusion dose of ADSCs, suggesting that the ineffectiveness of low-dose ADSCs in sepsis is at least in part due to insufficient regulation of bacterial clearance mediated by PBMCs. This evidence concerns the gene NR1H3 and Sepsis.