As a result, the rescue Tg males exhibited complete restoration of all parameters and events examined: infertility rate, percentage (%) hairpin sperm flagellum in the cauda epididymal and postcopulatory spermatozoa, reduction of AK1 and AK2, and reduction of sperm motility (Fig. 7, Fig. S12. The gene discussed is AK1; the disease is Infertility.