IFITM3 and influenza: Third, further exploration to include other SNPs is needed, such as the SNPs recently reported to affect disease severity (rs12252-C IFITM3)41; rs1755609, rs2438409 GLDC)41,42 and influenza vaccination (rs12252-C IFITM3; rs743811 HO-1, rs2160567 HO-2; rs10220412 IGHV1–69; rs8099917 IL-28B; rs17793951, rs1175540, rs2972164 PPARG, rs2071045 LEP, rs876537 CRP; HLA gene polymorphism)7,43–47.