Measuring the levels of cytokines and chemokines in the BALF revealed an increase in the levels of macrophage inflammatory protein 1 alpha, IL-12, macrophage-derived chemokine, and keratinocyte-derived chemokine in the COPD group; this was attenuated upon administration of LLT or LS803. The gene discussed is CCL22; the disease is chronic obstructive pulmonary disease.