APGAR: Appearance, Pulse, Grimace, Activity, and Respiration; CRP: C-reactive Protein; LOS: Late onset sepsis; NICU: Neonatal intensive care unit; NVD: Natural Vaginal Delivery; PROM: Premature Rupture of Membranes; RDS: Respiratory Distress Syndrome; SD: Standard Deviation; WBC: white blood cells. The gene discussed is CRP; the disease is newborn respiratory distress syndrome.