CACNA1S and Dorfman-Chanarin disease: An analysis using the developmental single-cell gene expression data from the Descartes atlas [22], demonstrates how our previously trained models correctly predict the affected developmental tissues for several genes, including ABHD5 (associated with Chanarin-Dorfman syndrome, and predicted to affect the stomach and intestine), CACNA1S (predicted to affect muscles), FBN1 (Fibrillin-1, developing heart), FGFR2 (developing lungs), ITM2B (Cerebrum), TNNI3 (Troponin, in the developing heart).