By modulating the Phosphoinositide 3-kinase/Akt/mammalian target of rapamycin/p70S6 kinase (PI3K/Akt/mTOR/p70S6K) pathway and targeting insulin like growth factor1 receptor (IGF1R), Wang’s et al. research showed that miR-122 acts as a tumor suppressor and is crucial in preventing the growth of new tumors. The gene discussed is AKT1; the disease is neoplasm.