Here, the stat1−/− mice were highly susceptible to ZIKV infection, as indicated by a rapid loss of body weight and early death (< 7 days), while the stat1−/−clec5a−/− mice were less susceptible but not completely resistant to ZIKV infection, as exhibited by a slower loss of body weight and delayed death (Fig. 1a, b). The gene discussed is STAT1; the disease is Zika virus infectious disease.