HOXB9 and central nervous system cancer: High levels of HOXB9 are associated with a poor prognosis in lung adenocarcinoma patients [36], low overall survival in colon cancer [37], high cancer grade but low overall survival in breast cancer [38], clinical progression in glioma patients [39], gastric cancer tumor progression, vascular and lymphatic invasion [40], and low vascular invasion and overall survival in hepatocellular carcinoma patients [41].