AKT1 and cancer: The finding revealed that the signaling pathways related to immune checkpoints, PI3K/AKT, Janus kinase (JAK)/STAT, mitogen-activated protein kinase (MAPK), and cancer were significantly enriched in the group of high FCGBP expression (Figure 4B and 4C), suggesting the oncogenic role of FCGBP by regulating multiple targets and activating multiple signaling pathways in HCC.