AZU1 and ablepharon macrostomia syndrome: ROC curve analysis showed that FAM86B3P (AUC = 0.867, P = 0.007), AZU1 (AUC = 0.800, P = 0.027) and PRKCG (AUC = 0.822, P = 0.018) were good predictors of moderate to severe AMS.