In contrast, KEGG pathway analysis revealed that selected genes were mainly enriched in some metabolism-related pathways, including type II Diabetes Mellitus, insulin signaling pathway, starch and sucrose metabolism, and maturity-onset diabetes of the young (Fig. 4f), indicating the potential possibility that those differentiated genes were associated with metabolism syndrome of the offspring of GDM. The gene discussed is INS; the disease is type 2 diabetes mellitus.