ARHGAP15 and neoplasm: In IF staining, the tumor cells were recognized by human specific cytokeratin7 (CK7) antibody, the result of which showed that mice in ARHGAP15-transfected group had increased number of survived GC cells in lungs than that in control group at both 24hours and 7days post injection (Fig 3B, 3C and 3D), implying that ARHGAP15 played an important role in tumor metastatic colonization.