In the analysis for survival outcomes in patients with CRC using the Kaplan-Meier method, both overall and colorectal cancer-specific survival was not affected by MMR/MSI status, EGFR expression, and PD-L1 CPS level (S2 Fig), which could be originated from the small number of patients who expired during follow-up. This evidence concerns the gene EGFR and colorectal carcinoma.