Mutations in GORAB have been identified in cases of geroderma osteodysplastica (GO), a progeroid disorder characterised by wrinkled skin, joint laxity, osteoporosis, and growth retardation (Al-Dosari and Alkuraya, 2009; Hennies et al., 2008). Here, GORAB is linked to geroderma osteodysplastica.