AMPD3 and type 2 diabetes mellitus: We recently reported that upregulated expression of AMP deaminase 3 (AMPD3), a rate‐limiting enzyme in the purine nucleotide cycle, is involved in abnormal cardiac energetics in Otsuka Long‐Evans‐Tokushima fatty (OLETF) rats, models of type 2 diabetes (T2DM) (Igaki et al., 2021; Kouzu et al., 2015; Tatekoshi et al., 2018).