MAPT and Parkinson disease: The variables included into the models comprised demographic and clinical data, including MDS-UPDRS item-level data (86 variables at baseline; 217 including 3 month follow-up), CSF biomarkers (amyloid beta, phosphorylated tau, total tau), blood serum transcriptomic data (7 variables), 3472 SNPs gained through a linkage disequilibrium analysis of an initial set of 145 PD associated SNPs obtained from DisGeNET13, and brain region specific DaTSCAN (5 variables).