In this study, sesamin, quercetin, bicuculline, kaempferol, luteolin, and ginkgolide B were identified as important herbal compounds, and EGFR, CREB1, PTGS2, PPARG, PPARA, MMP9, MAPK8, and MAPK14 were identified as major protein targets for the treatment of CA. The gene discussed is MAPK8; the disease is cancer.