BRD2 and polycystic ovary syndrome: In comparison with PCOS women with anovulatory phenotypes, these oligo-ovulatory women appear to have a different metabolic and hormonal profile.[23,24] The oligo-ovulatory woman may exhibit milder symptoms and a less severe phenotype than anovulatory women, namely lower serum testosterone, androstenedione, and free androgen index.[16] Patients with anovulatory disorders tend to be hyperandrogenic, so they are less sensitive to endogenous FSH.[25] There may be an explanation for the higher cycle cancelation rates in the anovulatory group and the longer additional Gn use time.