The levels of glomerular sclerosis, renal interstitial fibrosis, acute tubular injury, urinary N-acetyl-β-D-glucosaminidase (NAG), urinary retinol binding protein (RBP), blood C-reactive protein (CRP), hypokalemia, hypophosphatemia, and hypernatremia and the positive proportion of blood PLA2R antibody in MN patients with baseline anemia were higher than those in patients with baseline non-anemia (p < 0.05). The gene discussed is CRP; the disease is anemia.