TEG was found to be most suitable for distinguishing moderate from mild hemophilia A, whereas TGAs and clot waveform analysis were more accurate in identifying people with more severe hemophilia A. Heterogeneity of thrombin potential was observed with each of the global assays, indicating that the amount and rate of thrombin generated was not solely dependent on the amount of FVIII in the samples [29]. The gene discussed is F8; the disease is hemophilia A.