GPLD1 and neoplasm: In the study of Zhang et al., they found that after pretreatment with TsIIA, the vascular wall structure of tumor tissue was better, the pericellular coverage increased, and the contact between basement membrane and endothelial cells increased, which reduced the outflow of polyethylene glycol liposome doxorubicin (PLD), increased the distribution concentration of PLD, and promoted its anti-tumor effect (136).