The ROC was utilized to investigate the diagnostic value of INSL6 in pancancer, which demonstrated that INSL6 expression can predict 12 cancer types (area under the curve (AUC) > 0.6), including BRCA, ESCA, LUSC, OV, TGCT, STAD, KIRP, LAML, LIHC, KIRC, KICH, and COAD (Figure 4; Figure S2). This evidence concerns the gene INSL6 and cancer.