After injected CTL induced KIF-20A-LPs, expression of KIF20A was detected in 55% of HNMT, KIF20A specific Th1 cell response was detected after short-term stimulation of PBMC in 50% of HNMT patients, indicated that KIF20A-LP can induce tumor-specific Th1 cells and CTLs at the same time [67]. This evidence concerns the gene KIF20A and neoplasm.