The POSEIDON criteria divide infertile patients into four groups according to age, anti-mullerian hormone (AMH), and antral follicle count (AFC): Group 1: patients aged below 35 years with a good ovarian reserve (AFC ≥ 5, AMH ≥ 1.2 ng/mL) but unexpected POR. The gene discussed is AMH; the disease is Infertility.