Although the results of some studies on the role of FOXA appear to be relative:the glucagon-like peptide-1 receptor (GLP-1R) agonist Exendin-4 leads to reduced expression of FOXA1 via the Wnt/Β-catenin pathway, further resulting in a decrease in FABP1, which causes a reduction in fatty acid uptake and prevents the development of hepatic steatosis (105), which seems contradictory to the reduction in fatty acid uptake by FOXA1 found in in vitro experiments. This evidence concerns the gene FOXA1 and Hepatic steatosis.