Microrod-treated animals had significantly higher changes in stroke volume compared to saline and free decorin groups (p < 0.05 and p< 0.01, respectively) while decorin microrods showcased a trend towards increased change in stroke volume when compared to both vehicle and free decorin (Fig. 3E, p = 0.1772, p= 0.0595, respectively). Here, DCN is linked to stroke disorder.