We have successfully utilized PEG microrods to locally deliver E-domain peptide and β-NGF to injured tissue in myocardial infarction and tibial fracture models.14,15 To enhance efficacy of our microrod platform for applications in post-MI therapy, we investigated the ability for microrods to locally deliver decorin, a SLRP with both antifibrotic and antioxidant attributes. Here, DCN is linked to myocardial infarction.