Consistent with the results from our survival analysis, overexpression of LRRC3B was associated with infiltration of anti-tumor immune cells (Figure 4D), including B cells, CD4+ T cells, CD8+ T cells and antigen presentation cell, while it suppressed the levels of infiltrating M2 macrophages, MDSCs, CAFs, and Tregs (Figure 4E). Here, CD4 is linked to neoplasm.