CD28 and cancer: LRRC3B expression was negatively correlated with most chemokines (CXCL1/2/3/5/6/8/9/10, CCL20, and CCL28) in more than 18 cancers, positively correlated with immunostimulators (CD27, CD28, CD40, TNFRSF13B, TNFRSF8/9, and TNFSF13) and MHC I/II modules, especially in KICH, COAD, BLCA, PRAD, PCPG, READ, and SCKM (Figures 4A-C).