Together, these results demonstrate that tumor exosomal cSERPINE2 promotes the secretion of IL-6 in TAMs by activating the NF-\documentclass[12pt]{minimal}\usepackage{amsmath}\usepackage{wasysym}\usepackage{amsfonts}\usepackage{amssymb}\usepackage{amsbsy}\usepackage{mathrsfs}\usepackage{upgreek}\setlength{\oddsidemargin}{-69pt}\begin{document}$$\upkappa$$\end{document}κB pathway to encourage breast cancer progression. The gene discussed is IL6; the disease is neoplasm.