IL6 and neoplasm: Our findings demonstrated that tumor exosomal cSERPINE2 increased IL-6 levels by activating the NF-\documentclass[12pt]{minimal}\usepackage{amsmath}\usepackage{wasysym}\usepackage{amsfonts}\usepackage{amssymb}\usepackage{amsbsy}\usepackage{mathrsfs}\usepackage{upgreek}\setlength{\oddsidemargin}{-69pt}\begin{document}$$\upkappa$$\end{document}κB pathway of TAMs and that blocking IL-6 reversed the tumor-promoting effect of cSERPINE2 overexpression in vivo.