Notably, MALT1 drives epithelial-to-mesenchymal transition (EMT) in claudin-low, triple-negative breast cancer (TNBC) with overexpression of selected G protein-coupled receptors (GPCRs) [50], suggesting MALT1 as a novel oncogenic signaling molecule in a subset of GPCR+TNBCs. Here, MALT1 is linked to triple-negative breast carcinoma.