Mechanistically, tumor exosomal cSERPINE2 was shuttled to TAMs and notably elevated MALT1 levels, enhancing the secretion of Interleukin-6 (IL-6) by activating the NF-\documentclass[12pt]{minimal}\usepackage{amsmath}\usepackage{wasysym}\usepackage{amsfonts}\usepackage{amssymb}\usepackage{amsbsy}\usepackage{mathrsfs}\usepackage{upgreek}\setlength{\oddsidemargin}{-69pt}\begin{document}$$\upkappa$$\end{document}κB pathway and leading to increased proliferation and invasion of breast cancer cells. This evidence concerns the gene MALT1 and breast cancer.