for example, tDR-1:30-Gly-GCC-2-M10 (Gly-tRF), which was highly expressed in hepatocellular carcinoma (HCC) cell lines and tumor tissues, could activate the AKT signaling pathway to enhance liver cancer stem cells (LCSC)-like cell properties and promote the EMT progress through targeting NDFIP2 mRNA 3’ UTR in a miRNA-like manner [69]. The gene discussed is AKT1; the disease is hepatocellular carcinoma.