For instance, the lncRNA UICLM could induce its biological effects by regulating ZEB2, and ZEB2 depletion inhibits UICLM-promoted tumorigenesis [57]; MIR17HG promotes CRC progression via NF-κB/RELA pathway [43]; SNHG7 can compete against endogenous miR-34a and GALNT7, thereby activating PI3K/Akt/mTOR pathway to promote CRC proliferation and metastasis [56]; FLANC [8] and SNHG5 [54] are involved in STAT3 pathway for similar pathogenic functions. This evidence concerns the gene AKT1 and colorectal carcinoma.