In 2011, Xu et al. proved the importance of MALAT-1 in CRC metastasis; they analyzed the MALAT-1 gene expression in five fragments and found that one fragment (6918 nt-8441 nt) located at the 3’ end of MALAT-1 plays an important role in CRC cell proliferation, migration and invasion [67]. The gene discussed is MALAT1; the disease is colorectal carcinoma.