Therefore, enormous clinical effort has been made to identify any potential risk factors for CAA formation, including sex [26], strategy of IVIG treatment [26], IVIG resistance [27], duration of fever [27], extreme age (< 1 year or > 9 years) [28, 29], tachycardia [30], and any changes in blood test results of increased C-reactive protein (CRP) [26, 31], n-terminal pro-brain natriuretic peptide [32], neutrophil-to-lymphocyte ratio [31], hypoalbuminemia, total bilirubin, and platelet count. The gene discussed is CRP; the disease is Hypoalbuminemia.