As shown in Table 3, there were only significant associations between PKM2 and HER2 status (p = 0.001) and DCIS (p = 0.046) in HR-ve tumors, and with HER2 status (p < 0.001) and SP expression level (p = 0.012) in HR + ve tumors. This evidence concerns the gene ERBB2 and ductal breast carcinoma in situ.