Of all potential biomarkers associated with AKI persistence (i.e., apoptosis, necrosis, endothelial injury, cell–cell and cell–matrix adhesion, cytoprotection, oxidative processes, cell cycle regulation, inflammation, kidney injury, immune function, and fibrosis), the researchers found that CCL14 had the highest ability to predict AKI persistence with an AUC of 0.83, which outpaced other biomarkers markers (i.e., urinary Chitinase3-Like1 and plasma cystatin). This evidence concerns the gene CST4 and acute kidney injury.